Anti-ATOH1 antibody (215-354) (STJ28613)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ATOH1 (215-354) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATOH1 |
| Gene ID | 474 |
| Uniprot ID | ATOH1_HUMAN |
| Immunogen Region | 215-354 |
| Immunogen Sequence | LQTPSGGEQPPPPPASCKSD HHHLRTAASYEGGAGNATAA GAQQASGGSQRPTPPGSCRT RFSAPASAGGYSVQLDALHF STFEDSALTAMMAQKNLSPS LPGSILQPVQEENSKTSPRS HRSDGEFSPHSHYSDSDEAS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 215-354 of human ATOH1 (NP_005163.1). |
Additional Info
| Function | Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. |
| Protein Name | Transcription Factor Atoh1Atonal Bhlh Transcription Factor 1Class A Basic Helix-Loop-Helix Protein 14Bhlha14Helix-Loop-Helix Protein Hath-1Hath1Protein Atonal Homolog 1 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Atoh1 antibodyAnti-Atonal Bhlh Transcription Factor 1 antibodyAnti-Class A Basic Helix-Loop-Helix Protein 14 antibodyAnti-Bhlha14 antibodyAnti-Helix-Loop-Helix Protein Hath-1 antibodyAnti-Hath1 antibodyAnti-Protein Atonal Homolog 1 antibodyAnti-ATOH1 antibodyAnti-ATH1 antibodyAnti-BHLHA14 antibody |
Information sourced from Uniprot.org