| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ATOH1 |
| Gene ID: | 474 |
| Uniprot ID: | ATOH1_HUMAN |
| Immunogen Region: | 215-354 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 215-354 of human ATOH1 (NP_005163.1). |
| Immunogen Sequence: | LQTPSGGEQPPPPPASCKSD HHHLRTAASYEGGAGNATAA GAQQASGGSQRPTPPGSCRT RFSAPASAGGYSVQLDALHF STFEDSALTAMMAQKNLSPS LPGSILQPVQEENSKTSPRS HRSDGEFSPHSHYSDSDEAS |
| Function | Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription. |
| Protein Name | Transcription Factor Atoh1Atonal Bhlh Transcription Factor 1Class A Basic Helix-Loop-Helix Protein 14Bhlha14Helix-Loop-Helix Protein Hath-1Hath1Protein Atonal Homolog 1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Atoh1 antibodyAnti-Atonal Bhlh Transcription Factor 1 antibodyAnti-Class A Basic Helix-Loop-Helix Protein 14 antibodyAnti-Bhlha14 antibodyAnti-Helix-Loop-Helix Protein Hath-1 antibodyAnti-Hath1 antibodyAnti-Protein Atonal Homolog 1 antibodyAnti-ATOH1 antibodyAnti-ATH1 antibodyAnti-BHLHA14 antibody |
Information sourced from Uniprot.org