Anti-ATG10 antibody (204-220) (STJ29527)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ATG10 (204-220) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATG10 |
| Gene ID | 83734 |
| Uniprot ID | ATG10_HUMAN |
| Immunogen Region | 204-220 |
| Immunogen Sequence | GRPLTLKDIWEGVHECYKMR LLQGPWDTITQQEHPILGQP FFVLHPCKTNEFMTPVLKNS QKINKNVNYITSWLSIVGPV VGLNLPLSYAKATSQDERNV P |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 120-220 of human ATG10 (NP_113670.1). |
Additional Info
| Function | E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3. Plays a role in adenovirus-mediated cell lysis. |
| Protein Name | Ubiquitin-Like-Conjugating Enzyme Atg10Autophagy-Related Protein 10Apg10-Like |
| Database Links | Reactome: R-HSA-1632852 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ubiquitin-Like-Conjugating Enzyme Atg10 antibodyAnti-Autophagy-Related Protein 10 antibodyAnti-Apg10-Like antibodyAnti-ATG10 antibodyAnti-APG10L antibodyAnti-PP12616 antibody |
Information sourced from Uniprot.org