| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S7MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ATAD2 |
| Gene ID: | 29028 |
| Uniprot ID: | ATAD2_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ATAD2 (Q6PL18). |
| Immunogen Sequence: | MVVLRSSLELHNHSAASATG SLDLSSDFLSLEHIGRRRLR SAGAAQKKPAATTAKAGDGS SVKEVETYHRTRALRSLRKD AQNSSDSSFEKNVEITEQLA |
| Tissue Specificity | Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors. |
| Function | May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells. |
| Protein Name | Atpase Family Aaa Domain-Containing Protein 2Aaa Nuclear Coregulator Cancer-Associated ProteinAncca |
| Database Links | Reactome: R-HSA-8866910 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Atpase Family Aaa Domain-Containing Protein 2 antibodyAnti-Aaa Nuclear Coregulator Cancer-Associated Protein antibodyAnti-Ancca antibodyAnti-ATAD2 antibodyAnti-L16 antibodyAnti-PRO2000 antibody |
Information sourced from Uniprot.org
