Anti-ATAD1 antibody (STJA0004608)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenFusion protein of human ATAD1
General Information
| Short Description | Rabbit polyclonal anti-Outer Mitochondrial Transmembrane Helix Translocase for use in WB, IHC and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | WB 1:500-1:2000, IHC 1:50-1:300 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | ATAD1 |
| Gene ID | 84896 |
| Uniprot ID | ATAD1_HUMAN |
| Immunogen | Fusion protein of human ATAD1 |
Additional Info
| Function | Outer mitochondrial translocase required to remove mislocalized tail-anchored transmembrane proteins on mitochondria. Specifically recognizes and binds tail-anchored transmembrane proteins: acts as a dislocase that mediates the ATP-dependent extraction of mistargeted tail-anchored transmembrane proteins from the mitochondrion outer membrane. Also plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane.these activities are ATPase-dependent. |
| Protein Name | Outer Mitochondrial Transmembrane Helix TranslocaseAtpase Family Aaa Domain-Containing Protein 1Hatad1Thorase |
| Database Links | Reactome: R-HSA-9603798 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Membrane ProteinPeroxisome MembranePostsynaptic Cell Membrane |
| Alternative Antibody Names | Anti-Outer Mitochondrial Transmembrane Helix Translocase antibodyAnti-Atpase Family Aaa Domain-Containing Protein 1 antibodyAnti-Hatad1 antibodyAnti-Thorase antibodyAnti-ATAD1 antibodyAnti-FNP001 antibody |
Information sourced from Uniprot.org