Anti-ASPH antibody (STJA0010213)

SKU:
STJA0010213
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Aspartyl/asparaginyl beta-hydroxylase for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:1000-2000
ELISA 1:5000-20000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:ASPH
Gene ID:444
Uniprot ID:ASPH_HUMAN
Immunogen:Synthesized peptide derived from human ASPH
Specificity:This antibody detects endogenous levels of Human, Mouse, Rat ASPH
Tissue Specificity Isoform 1 is detected in all tissues tested. Isoform 8 is mainly expressed in pancreas, heart, brain, kidney and liver. Isoform 8 is expressed in kidney (at protein level).
Function Isoform 1: Specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins. Isoform 8: Membrane-bound Ca(2+)-sensing protein, which is a structural component of the ER-plasma membrane junctions. Isoform 8 regulates the activity of Ca(+2) released-activated Ca(+2) (CRAC) channels in T-cells.
Protein Name Aspartyl/Asparaginyl Beta-Hydroxylase
Aspartate Beta-Hydroxylase
Asp Beta-Hydroxylase
Peptide-Aspartate Beta-Dioxygenase
Database Links Reactome: R-HSA-2672351
Reactome: R-HSA-5578775
Reactome: R-HSA-9629569
Cellular Localisation Isoform 1: Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Isoform 4: Sarcoplasmic Reticulum Membrane
Isoform 8: Endoplasmic Reticulum Membrane
Alternative Antibody Names Anti-Aspartyl/Asparaginyl Beta-Hydroxylase antibody
Anti-Aspartate Beta-Hydroxylase antibody
Anti-Asp Beta-Hydroxylase antibody
Anti-Peptide-Aspartate Beta-Dioxygenase antibody
Anti-ASPH antibody
Anti-BAH antibody

Information sourced from Uniprot.org