| Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance. Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism. Facilitates cellular uptake of long-chain free fatty acids. |
| Protein Name | Aspartate Aminotransferase - MitochondrialMaspatFatty Acid-Binding ProteinFabp-1Glutamate Oxaloacetate Transaminase 2Kynurenine Aminotransferase 4Kynurenine Aminotransferase IvKynurenine--Oxoglutarate Transaminase 4Kynurenine--Oxoglutarate Transaminase IvPlasma Membrane-Associated Fatty Acid-Binding ProteinFabppmTransaminase A |
| Database Links | Reactome: R-HSA-1614558Reactome: R-HSA-389661Reactome: R-HSA-8963693Reactome: R-HSA-8964539Reactome: R-HSA-9856872 |
| Cellular Localisation | Mitochondrion MatrixCell MembraneExposure To Alcohol Promotes Translocation To The Cell Membrane |
| Alternative Antibody Names | Anti-Aspartate Aminotransferase - Mitochondrial antibodyAnti-Maspat antibodyAnti-Fatty Acid-Binding Protein antibodyAnti-Fabp-1 antibodyAnti-Glutamate Oxaloacetate Transaminase 2 antibodyAnti-Kynurenine Aminotransferase 4 antibodyAnti-Kynurenine Aminotransferase Iv antibodyAnti-Kynurenine--Oxoglutarate Transaminase 4 antibodyAnti-Kynurenine--Oxoglutarate Transaminase Iv antibodyAnti-Plasma Membrane-Associated Fatty Acid-Binding Protein antibodyAnti-Fabppm antibodyAnti-Transaminase A antibodyAnti-GOT2 antibodyAnti-KYAT4 antibody |
Information sourced from Uniprot.org
