| Tissue Specificity | Widely expressed, with highest level in brain, heart and kidney. |
| Post Translational Modifications | Methylated at Gln-1220 by N6AMT1. |
| Function | Histone methyltransferase specifically trimethylating 'Lys-36' of histone H3 forming H3K36me3. Also monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro. The physiological significance of the H3K9me1 activity is unclear. |
| Protein Name | Histone-Lysine N-Methyltransferase Ash1lAsh1-Like ProteinHuash1Absent Small And Homeotic Disks Protein 1 HomologLysine N-Methyltransferase 2h |
| Database Links | Reactome: R-HSA-3214841 |
| Cellular Localisation | NucleusCell JunctionTight JunctionChromosomeThe Relevance Of Tight Junction Localization Is However Unclear |
| Alternative Antibody Names | Anti-Histone-Lysine N-Methyltransferase Ash1l antibodyAnti-Ash1-Like Protein antibodyAnti-Huash1 antibodyAnti-Absent Small And Homeotic Disks Protein 1 Homolog antibodyAnti-Lysine N-Methyltransferase 2h antibodyAnti-ASH1L antibodyAnti-KIAA1420 antibodyAnti-KMT2H antibody |
Information sourced from Uniprot.org
