| Tissue Specificity | Expressed exclusively in hepatic parenchymal cells. |
| Function | Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. |
| Protein Name | Asialoglycoprotein Receptor 2Asgp-R 2Asgpr 2C-Type Lectin Domain Family 4 Member H2Hepatic Lectin H2Hl-2 |
| Database Links | Reactome: R-HSA-446203 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Asialoglycoprotein Receptor 2 antibodyAnti-Asgp-R 2 antibodyAnti-Asgpr 2 antibodyAnti-C-Type Lectin Domain Family 4 Member H2 antibodyAnti-Hepatic Lectin H2 antibodyAnti-Hl-2 antibodyAnti-ASGR2 antibodyAnti-CLEC4H2 antibody |
Information sourced from Uniprot.org
