Anti-ASGR1 antibody (STJA0006900)

SKU:
STJA0006900
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Asialoglycoprotein receptor 1 is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ASGR1
Gene ID: 432
Uniprot ID: ASGR1_HUMAN
Specificity: This antibody detects endogenous levels of ASGR1 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human ASGR1
Post Translational Modifications Phosphorylated on a cytoplasmic Ser residue.
Function Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Protein Name Asialoglycoprotein Receptor 1
Asgp-R 1
Asgpr 1
C-Type Lectin Domain Family 4 Member H1
Hepatic Lectin H1
Hl-1
Database Links Reactome: R-HSA-446203
Cellular Localisation Isoform H1a: Membrane
Single-Pass Type Ii Membrane Protein
Isoform H1b: Secreted
Alternative Antibody Names Anti-Asialoglycoprotein Receptor 1 antibody
Anti-Asgp-R 1 antibody
Anti-Asgpr 1 antibody
Anti-C-Type Lectin Domain Family 4 Member H1 antibody
Anti-Hepatic Lectin H1 antibody
Anti-Hl-1 antibody
Anti-ASGR1 antibody
Anti-CLEC4H1 antibody

Information sourced from Uniprot.org

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