| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | Asb17 |
| Gene ID: | 66772 |
| Uniprot ID: | ASB17_MOUSE |
| Immunogen Region: | 78-177 |
| Immunogen Sequence: | GHRFELNFNLEFTEICVNTI LYWVFARKGNPDFVELLLKK TKDYVQDRSCSLALIWRTFT PVYCPSPLSGITPLLYVAQT RQSNILKILLQYGILEREKN |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 78-177 of mouse ASB17 (NP_080034.2). |
| Tissue Specificity | Specifically expressed in testis. Localizes to spermatogenic cells in testis, with highest expression in round spermatids and condensing spermatids and lower expression in pachytene spermatocytes. |
| Function | May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
| Protein Name | Ankyrin Repeat And Socs Box Protein 17Asb-17 |
| Database Links | Reactome: R-MMU-8951664Reactome: -MMU-983168 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ankyrin Repeat And Socs Box Protein 17 antibodyAnti-Asb-17 antibodyAnti-Asb17 antibody |
Information sourced from Uniprot.org
