| Tissue Specificity | Expressed in the eye. The highest expression is observed in the iris, with moderate levels in the trabecular meshwork (TM), the lamina, and the optic nerve.slightly lower levels in the ciliary body, retina, and choroid.and very low levels in the lens. |
| Function | May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
| Protein Name | Ankyrin Repeat And Socs Box Protein 10Asb-10 |
| Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmNucleusIn The Ciliary BodyIt Is Detected In The Cytoplasm And Perinuclear Region Of The Pigmented Ciliary Epithelial LayerIn The RetinaIt Is Detected In The Nuclei Of Retinal Ganglion Cells |
| Alternative Antibody Names | Anti-Ankyrin Repeat And Socs Box Protein 10 antibodyAnti-Asb-10 antibodyAnti-ASB10 antibody |
Information sourced from Uniprot.org
