| Post Translational Modifications | Phosphorylated on tyrosine residues by SRC and PTK2B. |
| Function | Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration. |
| Protein Name | Arf-Gap With Sh3 Domain - Ank Repeat And Ph Domain-Containing Protein 2Development And Differentiation-Enhancing Factor 2Paxillin-Associated Protein With Arf Gap Activity 3Pag3Pyk2 C-Terminus-Associated ProteinPap |
| Database Links | |
| Cellular Localisation | CytoplasmGolgi ApparatusGolgi Stack MembranePeripheral Membrane ProteinCell MembraneColocalizes With F-Actin And Arf6 In Phagocytic Cups |
| Alternative Antibody Names | Anti-Arf-Gap With Sh3 Domain - Ank Repeat And Ph Domain-Containing Protein 2 antibodyAnti-Development And Differentiation-Enhancing Factor 2 antibodyAnti-Paxillin-Associated Protein With Arf Gap Activity 3 antibodyAnti-Pag3 antibodyAnti-Pyk2 C-Terminus-Associated Protein antibodyAnti-Pap antibodyAnti-ASAP2 antibodyAnti-DDEF2 antibodyAnti-KIAA0400 antibody |
Information sourced from Uniprot.org
