| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ASAP2 (1-120) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ASAP2 |
| Gene ID: |
8853 |
| Uniprot ID: |
ASAP2_HUMAN |
| Immunogen Region: |
1-120 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human ASAP2 (NP_001128663). |
| Immunogen Sequence: |
MPDQISVSEFVAETHEDYKA PTASSFTTRTAQCRNTVAAI EEALDVDRMVLYKMKKSVKA INSSGLAHVENEEQYTQALE KFGGNCVCRDDPDLGSAFLK FSVFTKELTALFKNLIQNMN |
| Tissue Specificity | Detected in heart, brain, placenta, kidney, monocytes and pancreas. |
| Post Translational Modifications | Phosphorylated on tyrosine residues by SRC and PTK2B. |
| Function | Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration. |
| Protein Name | Arf-Gap With Sh3 Domain - Ank Repeat And Ph Domain-Containing Protein 2Development And Differentiation-Enhancing Factor 2Paxillin-Associated Protein With Arf Gap Activity 3Pag3Pyk2 C-Terminus-Associated ProteinPap |
| Cellular Localisation | CytoplasmGolgi ApparatusGolgi Stack MembranePeripheral Membrane ProteinCell MembraneColocalizes With F-Actin And Arf6 In Phagocytic Cups |
| Alternative Antibody Names | Anti-Arf-Gap With Sh3 Domain - Ank Repeat And Ph Domain-Containing Protein 2 antibodyAnti-Development And Differentiation-Enhancing Factor 2 antibodyAnti-Paxillin-Associated Protein With Arf Gap Activity 3 antibodyAnti-Pag3 antibodyAnti-Pyk2 C-Terminus-Associated Protein antibodyAnti-Pap antibodyAnti-ASAP2 antibodyAnti-DDEF2 antibodyAnti-KIAA0400 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
