| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Arylsulfatase B (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 45kDa band observed in Human Heart lysates (calculated MW of 46.0kDa according to NP_942002.1). Recommended concentration: 0.03-0.1µg/ml.An additional band of unknown identity w |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | ARSB |
| Gene ID: | 411 |
| Uniprot ID: | ARSB_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_000037.2; NP_942002.1 |
| Specificity: | This antibody is expected to recognise both reported isoforms (NP_000037.2; NP_942002.1). |
| Immunogen Sequence: | KLARGHTNGTKPLD |
| Function | Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation. Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium. In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels. |
| Protein Name | Arylsulfatase BAsbN-Acetylgalactosamine-4-SulfataseG4s |
| Database Links | Reactome: R-HSA-1663150Reactome: R-HSA-2024101Reactome: R-HSA-2206285Reactome: R-HSA-6798695Reactome: R-HSA-9840310 |
| Cellular Localisation | LysosomeCell Surface |
| Alternative Antibody Names | Anti-Arylsulfatase B antibodyAnti-Asb antibodyAnti-N-Acetylgalactosamine-4-Sulfatase antibodyAnti-G4s antibodyAnti-ARSB antibody |
Information sourced from Uniprot.org