Host: |
Goat |
Applications: |
Pep-ELISA/WB/IHC |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-Arylsulfatase B (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
WB-0.03-0.1µg/mlIHC-Recommended concentration, 5-10µg/mlELISA-antibody detection limit dilution 1:64000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
ARSB |
Gene ID: |
411 |
Uniprot ID: |
ARSB_HUMAN |
Immunogen Region: |
Internal |
Accession Number: |
NP_000037.2; NP_942002.1 |
Specificity: |
This antibody is expected to recognise both reported isoforms (NP_000037.2; NP_942002.1). |
Immunogen Sequence: |
KLARGHTNGTKPLD |
Function | Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation. Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium. In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels. |
Protein Name | Arylsulfatase BAsbN-Acetylgalactosamine-4-SulfataseG4s |
Database Links | Reactome: R-HSA-1660662Reactome: R-HSA-1663150Reactome: R-HSA-2024101Reactome: R-HSA-2206285Reactome: R-HSA-6798695 |
Cellular Localisation | LysosomeCell Surface |
Alternative Antibody Names | Anti-Arylsulfatase B antibodyAnti-Asb antibodyAnti-N-Acetylgalactosamine-4-Sulfatase antibodyAnti-G4s antibodyAnti-ARSB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance