Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Arylsulfatase K (481-530 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ARSK |
Gene ID: |
153642 |
Uniprot ID: |
ARSK_HUMAN |
Immunogen Region: |
481-530 aa |
Specificity: |
Arylsulfatase K Polyclonal Antibody detects endogenous levels of Arylsulfatase K protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human ARSK at the amino acid range 481-530 |
Post Translational Modifications | The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. The 75-kDa precursor undergoes proteolytic processing to yield a 23 kDa form. N-glycosylated with both high mannose and complex type sugars. |
Function | Catalyzes the hydrolysis of pseudosubstrates such as p-nitrocatechol sulfate and p-nitrophenyl sulfate. Catalyzes the hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate. Acts selectively on 2-sulfoglucuronate and lacks activity against 2-sulfoiduronate. |
Protein Name | Arylsulfatase KAskGlucuronate-2-SulfataseTelethon Sulfatase |
Database Links | Reactome: R-HSA-1660662Reactome: R-HSA-1663150 |
Cellular Localisation | SecretedLysosome |
Alternative Antibody Names | Anti-Arylsulfatase K antibodyAnti-Ask antibodyAnti-Glucuronate-2-Sulfatase antibodyAnti-Telethon Sulfatase antibodyAnti-ARSK antibodyAnti-TSULF antibodyAnti-UNQ630 antibodyAnti-PRO1246 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance