Anti-Arsk antibody (18-553 aa) (STJ11106942)

Name: Anti-Arsk antibody (18-553 aa) (STJ11106942)
SKU: STJ11106942
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11106942

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Short Description	Rabbit polyclonal Arsk (18-553 aa) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	Arsk
Gene ID	77041
Uniprot ID	ARSK_MOUSE
Immunogen Region	18-553 aa
Immunogen Sequence	APRTQKKRMQVNQAPNVVLV ASDSFDGRLTFQPGSQVVKL PFINFMRAHGTTFLNAYTNS PICCPSRAAMWSGLFTHLTE SWNNFKGLDPNYTTWMDIME KHGYQTQKFGKVDYTSGHHS ISNRVEAWTRDVAFLLRQEG RPIINLIPDKNRRRVMTKDW QNTDKAIEWLRQVNYTKPFV LYLGLNLPHPYPSPSSGENF GSSTFHTSLYWLEKVAYDAI KIPKWLTLSQMHPVDFYSS
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 18-553 of human Arsk (NP_084123.3).

Post Translational Modifications	The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. The 75-kDa precursor undergoes proteolytic processing to yield a 23 kDa form. N-glycosylated with both high mannose and complex type sugars.
Function	Catalyzes the hydrolysis of pseudosubstrates such as p-nitrocatechol sulfate and p-nitrophenyl sulfate. Catalyzes the hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate. Acts selectively on 2-sulfoglucuronate and lacks activity against 2-sulfoiduronate.
Protein Name	Arylsulfatase K Ask Glucuronate-2-Sulfatase
Database Links	Reactome: R-MMU-1663150 Reactome: -MMU-9840310
Cellular Localisation	Secreted Lysosome
Alternative Antibody Names	Anti-Arylsulfatase K antibody Anti-Ask antibody Anti-Glucuronate-2-Sulfatase antibody Anti-Arsk antibody

Information sourced from Uniprot.org