| Post Translational Modifications | The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. The 75-kDa precursor undergoes proteolytic processing to yield a 23 kDa form. N-glycosylated with both high mannose and complex type sugars. |
| Function | Catalyzes the hydrolysis of pseudosubstrates such as p-nitrocatechol sulfate and p-nitrophenyl sulfate. Catalyzes the hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate. Acts selectively on 2-sulfoglucuronate and lacks activity against 2-sulfoiduronate. |
| Protein Name | Arylsulfatase KAskGlucuronate-2-Sulfatase |
| Database Links | Reactome: R-MMU-1663150Reactome: -MMU-9840310 |
| Cellular Localisation | SecretedLysosome |
| Alternative Antibody Names | Anti-Arylsulfatase K antibodyAnti-Ask antibodyAnti-Glucuronate-2-Sulfatase antibodyAnti-Arsk antibody |
Information sourced from Uniprot.org
