| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Arylsulfatase I (311-360 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:40000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ARSI |
| Gene ID: | 340075 |
| Uniprot ID: | ARSI_HUMAN |
| Immunogen Region: | 311-360 aa |
| Specificity: | Arylsulfatase I Polyclonal Antibody detects endogenous levels of Arylsulfatase I protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ARSI at the amino acid range 311-360 |
| Post Translational Modifications | The oxidation of Cys-93 residue to 3-oxoalanine (also known as C(alpha)-formylglycine) by SUMF1/Sulfatase-modifying factor 1, seems critical for catalytic activity. |
| Function | Displays arylsulfatase activity at neutral pH, when co-expressed with SUMF1.arylsulfatase activity is measured in the secretion medium of retinal cell line, but no activity is recorded when measured in cell extracts. Lacks arylsulfatase activity. |
| Protein Name | Arylsulfatase IAsi |
| Database Links | Reactome: R-HSA-1663150Reactome: R-HSA-9840310 |
| Cellular Localisation | SecretedEndoplasmic ReticulumLocalized In The Intracellular Granular Structures |
| Alternative Antibody Names | Anti-Arylsulfatase I antibodyAnti-Asi antibodyAnti-ARSI antibody |
Information sourced from Uniprot.org