| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ARSA (210-509) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ARSA |
| Gene ID: |
410 |
| Uniprot ID: |
ARSA_HUMAN |
| Immunogen Region: |
210-509 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 210-509 of human ARSA (NP_000478.3). |
| Immunogen Sequence: |
LMADAQRQDRPFFLYYASHH THYPQFSGQSFAERSGRGPF GDSLMELDAAVGTLMTAIGD LGLLEETLVIFTADNGPETM RMSRGGCSGLLRCGKGTTYE GGVREPALAFWPGHIAPGVT HELASSLDLLPTLAALAGAP LPNVTLDGFDLSPLLLGTGK SPRQSLFFYPSYPDEVRGVF AVRTGKYKAHFFTQGSAHSD TTADPACHASSSLTAHEPPL LYDLSKDPGENYNLLGGVA |
| Post Translational Modifications | The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. This post-translational modification is severely defective in multiple sulfatase deficiency (MSD). |
| Function | Hydrolyzes cerebroside sulfate. |
| Protein Name | Arylsulfatase AAsaCerebroside-Sulfatase Cleaved Into - Arylsulfatase A Component B - Arylsulfatase A Component C |
| Database Links | Reactome: R-HSA-1660662Reactome: R-HSA-1663150Reactome: R-HSA-6798695 |
| Cellular Localisation | Endoplasmic ReticulumLysosome |
| Alternative Antibody Names | Anti-Arylsulfatase A antibodyAnti-Asa antibodyAnti-Cerebroside-Sulfatase Cleaved Into - Arylsulfatase A Component B - Arylsulfatase A Component C antibodyAnti-ARSA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
