• Western blot analysis of extracts of various cell lines, using ARSA antibody (STJ22695) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Anti-ARSA antibody (210-509) (STJ22695)

SKU:
STJ22695

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ARSA (210-509) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ARSA
Gene ID: 410
Uniprot ID: ARSA_HUMAN
Immunogen Region: 210-509
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 210-509 of human ARSA (NP_000478.3).
Immunogen Sequence: LMADAQRQDRPFFLYYASHH THYPQFSGQSFAERSGRGPF GDSLMELDAAVGTLMTAIGD LGLLEETLVIFTADNGPETM RMSRGGCSGLLRCGKGTTYE GGVREPALAFWPGHIAPGVT HELASSLDLLPTLAALAGAP LPNVTLDGFDLSPLLLGTGK SPRQSLFFYPSYPDEVRGVF AVRTGKYKAHFFTQGSAHSD TTADPACHASSSLTAHEPPL LYDLSKDPGENYNLLGGVA
Post Translational Modifications The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. This post-translational modification is severely defective in multiple sulfatase deficiency (MSD).
Function Hydrolyzes cerebroside sulfate.
Protein Name Arylsulfatase A
Asa
Cerebroside-Sulfatase Cleaved Into - Arylsulfatase A Component B - Arylsulfatase A Component C
Database Links Reactome: R-HSA-1660662
Reactome: R-HSA-1663150
Reactome: R-HSA-6798695
Cellular Localisation Endoplasmic Reticulum
Lysosome
Alternative Antibody Names Anti-Arylsulfatase A antibody
Anti-Asa antibody
Anti-Cerebroside-Sulfatase Cleaved Into - Arylsulfatase A Component B - Arylsulfatase A Component C antibody
Anti-ARSA antibody

Information sourced from Uniprot.org

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