• Western blot analysis of extracts of various cell lines, using ARSA antibody (STJ22695) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Anti-ARSA antibody (210-509) (STJ22695)

SKU:
STJ22695

£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ARSA
Gene ID: 410
Uniprot ID: ARSA_HUMAN
Immunogen Region: 210-509
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 210-509 of human ARSA (NP_000478.3).
Immunogen Sequence: LMADAQRQDRPFFLYYASHH THYPQFSGQSFAERSGRGPF GDSLMELDAAVGTLMTAIGD LGLLEETLVIFTADNGPETM RMSRGGCSGLLRCGKGTTYE GGVREPALAFWPGHIAPGVT HELASSLDLLPTLAALAGAP LPNVTLDGFDLSPLLLGTGK SPRQSLFFYPSYPDEVRGVF AVRTGKYKAHFFTQGSAHSD TTADPACHASSSLTAHEPPL LYDLSKDPGENYNLLGGVA
Post Translational Modifications The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. This post-translational modification is severely defective in multiple sulfatase deficiency (MSD).
Function Hydrolyzes cerebroside sulfate.
Protein Name Arylsulfatase A
Asa
Cerebroside-Sulfatase Cleaved Into - Arylsulfatase A Component B - Arylsulfatase A Component C
Database Links Reactome: R-HSA-1663150
Reactome: R-HSA-6798695
Reactome: R-HSA-9840310
Cellular Localisation Endoplasmic Reticulum
Lysosome
Alternative Antibody Names Anti-Arylsulfatase A antibody
Anti-Asa antibody
Anti-Cerebroside-Sulfatase Cleaved Into - Arylsulfatase A Component B - Arylsulfatase A Component C antibody
Anti-ARSA antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance