Anti-ARRDC4 antibody (300-400) (STJ11100473)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ARRDC4 (300-400) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ARRDC4 |
| Gene ID | 91947 |
| Uniprot ID | ARRD4_HUMAN |
| Immunogen Region | 300-400 |
| Immunogen Sequence | PGAKKLMLELPLVIGTIPYN GFGSRNSSIASQFSMDMSWL TLTLPEQPEAPPNYADVVSE EEFSRHIPPYPQPPNCEGEV CCPVFACIQEFRFQPPPLYS E |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human ARRDC4 (NP_899232.2). |
Additional Info
| Function | Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates. Plays a role in endocytosis of activated G protein-coupled receptors (GPCRs) (Probable). Through an ubiquitination-dependent mechanism also plays a role in the incorporation of SLC11A2 into extracellular vesicles. May play a role in glucose uptake. Participates in innate immune response by promoting IFIH1/MDA5 activation through interaction with TRIM65. |
| Protein Name | Arrestin Domain-Containing Protein 4 |
| Database Links | |
| Cellular Localisation | Early EndosomeCell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmic VesicleAlso Found In Extracellular Vesicles Different From Exosomes |
| Alternative Antibody Names | Anti-Arrestin Domain-Containing Protein 4 antibodyAnti-ARRDC4 antibody |
Information sourced from Uniprot.org