| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ARPC1A |
| Gene ID: | 10552 |
| Uniprot ID: | ARC1A_HUMAN |
| Immunogen Region: | 171-350 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 171-350 of human ARPC1A (NP_006400.2). |
| Immunogen Sequence: | AYIKEVDEKPASTPWGSKMP FGQLMSEFGGSGTGGWVHGV SFSASGSRLAWVSHDSTVSV ADASKSVQVSTLKTEFLPLL SVSFVSENSVVAAGHDCCPM LFNYDDRGCLTFVSKLDIPK QSIQRNMSAMERFRNMDKRA TTEDRNTALETLHQNSITQV SIYEVDKQDCRKFCTTGIDG |
| Function | Probably functions as a component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. |
| Protein Name | Actin-Related Protein 2/3 Complex Subunit 1aSop2-Like Protein |
| Database Links | Reactome: R-HSA-2029482Reactome: R-HSA-3928662Reactome: R-HSA-5663213Reactome: R-HSA-8856828Reactome: R-HSA-9664422 |
| Cellular Localisation | CytoplasmCytoskeletonNucleus |
| Alternative Antibody Names | Anti-Actin-Related Protein 2/3 Complex Subunit 1a antibodyAnti-Sop2-Like Protein antibodyAnti-ARPC1A antibodyAnti-SOP2L antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and TIMM17A knockout (KO) 293T cells, using [KO Validated] TIMM17A Rabbit polyclonal antibody (STJ11100794) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89730/358208/STJ11100794_1__30814.1713122530.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and TIMM17A knockout (KO) 293T cells, using [KO Validated] TIMM17A Rabbit polyclonal antibody (STJ11100794) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
![Western blot analysis of lysates from wild type (WT) and TIMM17A knockout (KO) 293T cells, using [KO Validated] TIMM17A Rabbit polyclonal antibody (STJ11100793) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89729/358207/STJ11100793_1__87381.1713122529.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and TIMM17A knockout (KO) 293T cells, using [KO Validated] TIMM17A Rabbit polyclonal antibody (STJ11100793) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
