| Host: | Rabbit |
| Applications: | WB/IP/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ARID2 |
| Gene ID: | 196528 |
| Uniprot ID: | ARID2_HUMAN |
| Immunogen Region: | 1586-1835 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1586-1835 of human ARID2 (NP_689854.2). |
| Immunogen Sequence: | QNVVPQNTPMPPSPAVQVQG QPNSSQPSPFSGSSQPGDPM RKPGQNFMCLWQSCKKWFQT PSQVFYHAATEHGGKDVYPG QCLWEGCEPFQRQRFSFITH LQDKHCSKDALLAGLKQDEP GQAGSQKSSTKQPTVGGTSS TPRAQKAIVNHPSAALMALR RGSRNLVFRDFTDEKEGPIT KHIRLTAALILKNIGKYSEC GRRLLKRHENNLSVLAISNM EASSTLAKCLYELNFTVQS |
| Tissue Specificity | Highly expressed in heart. |
| Function | Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes. |
| Protein Name | At-Rich Interactive Domain-Containing Protein 2Arid Domain-Containing Protein 2Brg1-Associated Factor 200Baf200Zinc Finger Protein With Activation PotentialZipzap/P200 |
| Database Links | Reactome: R-HSA-3214858Reactome: R-HSA-8939243 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-At-Rich Interactive Domain-Containing Protein 2 antibodyAnti-Arid Domain-Containing Protein 2 antibodyAnti-Brg1-Associated Factor 200 antibodyAnti-Baf200 antibodyAnti-Zinc Finger Protein With Activation Potential antibodyAnti-Zipzap/P200 antibodyAnti-ARID2 antibodyAnti-BAF200 antibodyAnti-KIAA1557 antibody |
Information sourced from Uniprot.org