Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-ARHGEF3 (287-526) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ARHGEF3 |
Gene ID: |
50650 |
Uniprot ID: |
ARHG3_HUMAN |
Immunogen Region: |
287-526 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 287-526 of human ARHGEF3 (NP_062455.1). |
Immunogen Sequence: |
LEEAINIIQGIVAEINTKTG ESECRYYKERLLYLEEGQKD SLIDSSRVLCCHGELKNNRG VKLHVFLFQEVLVITRAVTH NEQLCYQLYRQPIPVKDLLL EDLQDGEVRLGGSLRGAFSN NERIKNFFRVSFKNGSQSQT HSLQANDTFNKQQWLNCIRQ AKETVLCAAGQAGVLDSEGS FLNPTTGSRELQGETKLEQM DQSDSESDCSMDTSEVSLDC ERMEQTDSSCGNSRHGESN |
Tissue Specificity | Widely expressed. Highest levels are found in adult brain and skeletal muscle. Lower levels are found in heart and kidney. |
Function | Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases. |
Protein Name | Rho Guanine Nucleotide Exchange Factor 3Exchange Factor Found In Platelets And Leukemic And Neuronal TissuesXpln |
Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-8980692Reactome: R-HSA-9013026 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Rho Guanine Nucleotide Exchange Factor 3 antibodyAnti-Exchange Factor Found In Platelets And Leukemic And Neuronal Tissues antibodyAnti-Xpln antibodyAnti-ARHGEF3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance