• Immunofluorescence analysis of paraffin-embedded mouse kidney using AQP3 Rabbit polyclonal antibody (STJ22660) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of paraffin-embedded human kidney using AQP3 Rabbit polyclonal antibody (STJ22660) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of paraffin-embedded rat kidney using AQP3 Rabbit polyclonal antibody (STJ22660) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Western blot analysis of various lysates using AQP3 Rabbit polyclonal antibody (STJ22660) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-AQP3 antibody (178-292) (STJ22660)

SKU:
STJ22660

£112.50 - £524.50
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: AQP3
Gene ID: 360
Uniprot ID: AQP3_HUMAN
Immunogen Region: 178-292
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 178-292 of human AQP3 (NP_004916.1).
Immunogen Sequence: IVDPYNNPVPRGLEAFTVGL VVLVIGTSMGFNSGYAVNPA RDFGPRLFTALAGWGSAVFT TGQHWWWVPIVSPLLGSIAG VFVYQLMIGCHLEQPPPSNE EENVKLAHVKHKEQI
Tissue Specificity Widely expressed in epithelial cells of kidney (collecting ducts) and airways, in keratinocytes, immature dendritic cells and erythrocytes. Isoform 2 is not detectable in erythrocytes at the protein level.
Function Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea. Also participates in cell permeability to H2O2 and H2O2-mediated signaling. In skin, transports glycerol to the epidermis and stratum corneum, where it maintains hydration, elasticity, and supports lipid biosynthesis for barrier repair. In kidney, contributes to the reabsorption of water, helping the body maintain proper fluid balance.
Protein Name Aquaporin-3
Aqp-3
Aquaglyceroporin-3
Database Links Reactome: R-HSA-432040
Reactome: R-HSA-432047
Reactome: R-HSA-9725554
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Basolateral Cell Membrane
Alternative Antibody Names Anti-Aquaporin-3 antibody
Anti-Aqp-3 antibody
Anti-Aquaglyceroporin-3 antibody
Anti-AQP3 antibody

Information sourced from Uniprot.org

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