Anti-APRIL antibody [R02-8J9] (STJA0037076)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human APRIL
General Information
| Short Description | Rabbit monoclonal anti-APRIL for use in WB, ICC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-8J9 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IF 1:50-1:200 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TNFSF13 |
| Gene ID | 8741 |
| Uniprot ID | TNF13_HUMAN |
| Immunogen | A synthesized peptide derived from human APRIL |
Additional Info
| Tissue Specificity | Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. |
| Post Translational Modifications | The precursor is cleaved by furin. |
| Function | Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 13A Proliferation-Inducing LigandAprilTnf- And Apol-Related Leukocyte Expressed Ligand 2Tall-2Tnf-Related Death Ligand 1Trdl-1Cd Antigen Cd256 |
| Database Links | Reactome: R-HSA-450520Reactome: R-HSA-5669034 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Ligand Superfamily Member 13 antibodyAnti-A Proliferation-Inducing Ligand antibodyAnti-April antibodyAnti-Tnf- And Apol-Related Leukocyte Expressed Ligand 2 antibodyAnti-Tall-2 antibodyAnti-Tnf-Related Death Ligand 1 antibodyAnti-Trdl-1 antibodyAnti-Cd Antigen Cd256 antibodyAnti-TNFSF13 antibodyAnti-APRIL antibodyAnti-TALL2 antibodyAnti-ZTNF2 antibodyAnti-UNQ383 antibodyAnti-PRO715 antibody |
Information sourced from Uniprot.org