| Short Description : | Rabbit polyclonal APOL1 (179-398) antibody for use in IHC-P and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | APOL1 |
| Gene ID: | 8542 |
| Uniprot ID: | APOL1_HUMAN |
| Immunogen Region: | 179-398 |
| Immunogen Sequence: | SGSLSISSGILTLVGMGLAP FTEGGSLVLLEPGMELGITA ALTGITSSTMDYGKKWWTQA QAHDLVIKSLDKLKEVREFL GENISNFLSLAGNTYQLTRG IGKDIRALRRARANLQSVPH ASASRPRVTEPISAESGEQV ERVNEPSILEMSRGVKLTDV APVSFFLVLDVVYLVYESKH LHEGAKSETAEELKKVAQEL EEKLNILNNNYKILQADQEL |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 179-398 of human APOL1 (NP_003652.2). |
| Tissue Specificity | Plasma. Found on APOA-I-containing high density lipoprotein (HDL3). Expressed in pancreas, lung, prostate, liver, placenta and spleen. |
| Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. |
| Function | May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. |
| Protein Name | Apolipoprotein L1Apolipoprotein LApo-LApolApolipoprotein L-IApol-I |
| Database Links | Reactome: R-HSA-2168880Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Apolipoprotein L1 antibodyAnti-Apolipoprotein L antibodyAnti-Apo-L antibodyAnti-Apol antibodyAnti-Apolipoprotein L-I antibodyAnti-Apol-I antibodyAnti-APOL1 antibodyAnti-APOL antibody |
Information sourced from Uniprot.org
