Anti-APOL1 antibody (179-398) (STJ110252)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal APOL1 (179-398) antibody for use in IHC-P and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | APOL1 |
| Gene ID | 8542 |
| Uniprot ID | APOL1_HUMAN |
| Immunogen Region | 179-398 |
| Immunogen Sequence | SGSLSISSGILTLVGMGLAP FTEGGSLVLLEPGMELGITA ALTGITSSTMDYGKKWWTQA QAHDLVIKSLDKLKEVREFL GENISNFLSLAGNTYQLTRG IGKDIRALRRARANLQSVPH ASASRPRVTEPISAESGEQV ERVNEPSILEMSRGVKLTDV APVSFFLVLDVVYLVYESKH LHEGAKSETAEELKKVAQEL EEKLNILNNNYKILQADQEL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 179-398 of human APOL1 (NP_003652.2). |
Additional Info
| Tissue Specificity | Plasma. Found on APOA-I-containing high density lipoprotein (HDL3). Expressed in pancreas, lung, prostate, liver, placenta and spleen. |
| Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. |
| Function | May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. |
| Protein Name | Apolipoprotein L1Apolipoprotein LApo-LApolApolipoprotein L-IApol-I |
| Database Links | Reactome: R-HSA-2168880Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Apolipoprotein L1 antibodyAnti-Apolipoprotein L antibodyAnti-Apo-L antibodyAnti-Apol antibodyAnti-Apolipoprotein L-I antibodyAnti-Apol-I antibodyAnti-APOL1 antibodyAnti-APOL antibody |
Information sourced from Uniprot.org