• Western blot analysis of extracts of mouse liver, using APOL1 antibody (STJ115338) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-APOL1 antibody (1-238) (STJ115338)

SKU:
STJ115338

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-APOL1 (1-238) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: APOL1
Gene ID: 8542
Uniprot ID: APOL1_HUMAN
Immunogen Region: 1-238
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-238 of human APOL1 (NP_003652.2).
Immunogen Sequence: MEGAALLRVSVLCIWMSALF LGVGVRAEEAGARVQQNVPS GTDTGDPQSKPLGDWAAGTM DPESSIFIEDAIKYFKEKVS TQNLLLLLTDNEAWNGFVAA AELPRNEADELRKALDNLAR QMIMKDKNWHDKGQQYRNWF LKEFPRLKSELEDNIRRLRA LADGVQKVHKGTTIANVVSG SLSISSGILTLVGMGLAPFT EGGSLVLLEPGMELGITAAL TGITSSTMDYGKKWWTQA
Tissue Specificity Plasma. Found on APOA-I-containing high density lipoprotein (HDL3). Expressed in pancreas, lung, prostate, liver, placenta and spleen.
Post Translational Modifications Phosphorylated by FAM20C in the extracellular medium.
Function May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.
Protein Name Apolipoprotein L1
Apolipoprotein L
Apo-L
Apol
Apolipoprotein L-I
Apol-I
Database Links Reactome: R-HSA-2168880
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Secreted
Alternative Antibody Names Anti-Apolipoprotein L1 antibody
Anti-Apolipoprotein L antibody
Anti-Apo-L antibody
Anti-Apol antibody
Anti-Apolipoprotein L-I antibody
Anti-Apol-I antibody
Anti-APOL1 antibody
Anti-APOL antibody

Information sourced from Uniprot.org

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