Host: | Goat |
Applications: | Pep-ELISA/WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Goat polyclonal antibody anti-APOH (145-157) is suitable for use in ELISA and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:1000. WB: Approx 50kDa band observed in Human Liver, Kidney and Placenta lysates (calculated MW of 38.3kDa according to NP_000033.2). The observed molecular weight corresponds to earlier findings |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | APOH |
Gene ID: | 350 |
Uniprot ID: | APOH_HUMAN |
Immunogen Region: | 145-157 |
Accession Number: | NP_000033.2 |
Immunogen Sequence: | PSIPTFATLRVYK |
Post Translational Modifications | N- and O-glycosylated. PubMed:6587378 also reports glycosylation on 'Asn-188' for their allele. |
Function | Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. |
Protein Name | Beta-2-Glycoprotein 1 Apc Inhibitor Activated Protein C-Binding Protein Anticardiolipin Cofactor Apolipoprotein H Apo-H Beta-2-Glycoprotein I B2gpi Beta(2gpi |
Database Links | Reactome: R-HSA-114608 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Beta-2-Glycoprotein 1 antibody Anti-Apc Inhibitor antibody Anti-Activated Protein C-Binding Protein antibody Anti-Anticardiolipin Cofactor antibody Anti-Apolipoprotein H antibody Anti-Apo-H antibody Anti-Beta-2-Glycoprotein I antibody Anti-B2gpi antibody Anti-Beta(2gpi antibody Anti-APOH antibody Anti-B2G1 antibody |
Information sourced from Uniprot.org