• Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Anti-APOC1 antibody (1-50 aa) (STJ196507)

SKU:
STJ196507

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Apolipoprotein C-I (1-50 aa) is suitable for use in Immunohistochemistry and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-200
ELISA-Pep 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: APOC1
Gene ID: 341
Uniprot ID: APOC1_HUMAN
Immunogen Region: 1-50 aa
Specificity: This antibody detects endogenous levels of human APOC1
Immunogen: Synthesized peptide derived from the human APOC1 at the amino acid range 1-50
Function Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
Protein Name Apolipoprotein C-I
Apo-Ci
Apoc-I
Apolipoprotein C1 Cleaved Into - Truncated Apolipoprotein C-I
Database Links Reactome: R-HSA-8866423
Reactome: R-HSA-8964046
Reactome: R-HSA-9029569
Cellular Localisation Secreted
Alternative Antibody Names Anti-Apolipoprotein C-I antibody
Anti-Apo-Ci antibody
Anti-Apoc-I antibody
Anti-Apolipoprotein C1 Cleaved Into - Truncated Apolipoprotein C-I antibody
Anti-APOC1 antibody

Information sourced from Uniprot.org

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