Anti-APOBEC2 antibody (1-224) (STJ11100583)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal APOBEC2 (1-224) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | APOBEC2 |
| Gene ID | 10930 |
| Uniprot ID | ABEC2_HUMAN |
| Immunogen Region | 1-224 |
| Immunogen Sequence | MAQKEEAAVATEAASQNGED LENLDDPEKLKELIELPPFE IVTGERLPANFFKFQFRNVE YSSGRNKTFLCYVVEAQGKG GQVQASRGYLEDEHAAAHAE EAFFNTILPAFDPALRYNVT WYVSSSPCAACADRIIKTLS KTKNLRLLILVGRLFMWEEP EIQAALKKLKEAGCKLRIMK PQDFEYVWQNFVEQEEGESK AFQPWEDIQENFLYYEEKLA DILK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human APOBEC2 (NP_006780.1). |
Additional Info
| Tissue Specificity | Expressed exclusively in heart and skeletal muscle. |
| Function | Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. |
| Protein Name | C->U-Editing Enzyme Apobec-2Mrna(Cytosine(6666 Deaminase 2 |
| Database Links | Reactome: R-HSA-72200Reactome: R-HSA-75094 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-C->U-Editing Enzyme Apobec-2 antibodyAnti-Mrna(Cytosine(6666 Deaminase 2 antibodyAnti-APOBEC2 antibody |
Information sourced from Uniprot.org