| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-APOA4 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000. WB: Approx 45kDa band observed in Human Duodenum lysates (calculated MW of 45.4kDa according to NP_000473.2). Recommended concentration: 0.01-0.03µg/ml. Primary incubation was 1 hour. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | APOA4 |
| Gene ID: | 337 |
| Uniprot ID: | APOA4_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_000473.2 |
| Immunogen Sequence: | KEKESQDKTLSLP |
| Post Translational Modifications | Phosphorylation sites are present in the extracellular medium. |
| Function | May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II.potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. |
| Protein Name | Apolipoprotein A-Iv Apo-Aiv Apoa-Iv Apolipoprotein A4 |
| Database Links | Reactome: R-HSA-8963888 Reactome: R-HSA-8963889 Reactome: R-HSA-8963901 Reactome: R-HSA-975634 Reactome: R-HSA-977225 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Apolipoprotein A-Iv antibody Anti-Apo-Aiv antibody Anti-Apoa-Iv antibody Anti-Apolipoprotein A4 antibody Anti-APOA4 antibody |
Information sourced from Uniprot.org