Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Monoclonal |
Clone ID: |
S5250RM |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
APOA4 |
Gene ID: |
337 |
Uniprot ID: |
APOA4_HUMAN |
Immunogen Region: |
21-396 |
Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 21-396 of human APOA4 (NP_000473.2). |
Immunogen Sequence: |
EVSADQVATVMWDYFSQLSN NAKEAVEHLQKSELTQQLNA LFQDKLGEVNTYAGDLQKKL VPFATELHERLAKDSEKLKE EIGKELEELRARLLPHANEV SQKIGDNLRELQQRLEPYAD QLRTQVSTQAEQLRRQLTPY AQRMERVLRENADSLQASLR PHADELKAKIDQNVEELKGR LTPYADEFKVKIDQTVEELR RSLAPYAQDTQEKLNHQLEG LTFQMKKNAEELKARISAS |
Tissue Specificity | Synthesized primarily in the intestine and secreted in plasma. |
Post Translational Modifications | Phosphorylation sites are present in the extracellular medium. |
Function | May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II.potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. |
Protein Name | Apolipoprotein A-IvApo-AivApoa-IvApolipoprotein A4 |
Database Links | Reactome: R-HSA-8963888Reactome: R-HSA-8963889Reactome: R-HSA-8963901Reactome: R-HSA-975634Reactome: R-HSA-977225 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Apolipoprotein A-Iv antibodyAnti-Apo-Aiv antibodyAnti-Apoa-Iv antibodyAnti-Apolipoprotein A4 antibodyAnti-APOA4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance