Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Methylthioribulose-1-phosphate dehydratase (133-183 aa) is suitable for use in Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | APIP |
Gene ID: | 51074 |
Uniprot ID: | MTNB_HUMAN |
Immunogen Region: | 133-183 aa |
Specificity: | This antibody detects endogenous levels of MTNB at Human/Mouse |
Immunogen: | Synthesized peptide derived from the human MTNB at the amino acid range 133-183 |
Function | Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death. |
Protein Name | Methylthioribulose-1-Phosphate DehydrataseMtru-1-P DehydrataseApaf1-Interacting ProteinHapip |
Database Links | Reactome: R-HSA-111458Reactome: R-HSA-1237112Reactome: R-HSA-9627069 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Methylthioribulose-1-Phosphate Dehydratase antibodyAnti-Mtru-1-P Dehydratase antibodyAnti-Apaf1-Interacting Protein antibodyAnti-Hapip antibodyAnti-APIP antibodyAnti-CGI-29 antibody |
Information sourced from Uniprot.org