• Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-APIP antibody (133-183 aa) (STJ194510)

SKU:
STJ194510

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Methylthioribulose-1-phosphate dehydratase (133-183 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: APIP
Gene ID: 51074
Uniprot ID: MTNB_HUMAN
Immunogen Region: 133-183 aa
Specificity: This antibody detects endogenous levels of MTNB at Human/Mouse
Immunogen: Synthesized peptide derived from the human MTNB at the amino acid range 133-183
Function Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.
Protein Name Methylthioribulose-1-Phosphate Dehydratase
Mtru-1-P Dehydratase
Apaf1-Interacting Protein
Hapip
Database Links Reactome: R-HSA-111458
Reactome: R-HSA-1237112
Reactome: R-HSA-9627069
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Methylthioribulose-1-Phosphate Dehydratase antibody
Anti-Mtru-1-P Dehydratase antibody
Anti-Apaf1-Interacting Protein antibody
Anti-Hapip antibody
Anti-APIP antibody
Anti-CGI-29 antibody

Information sourced from Uniprot.org

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