| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (430-510 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
APBB1IP |
| Gene ID: |
54518 |
| Uniprot ID: |
AB1IP_HUMAN |
| Immunogen Region: |
430-510 aa |
| Specificity: |
RIAM Polyclonal Antibody detects endogenous levels of RIAM protein. |
| Immunogen: |
Synthesized peptide derived from RIAM at the amino acid range 430-510 |
| Function | Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion. |
| Protein Name | Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting ProteinApbb1-Interacting Protein 1Proline-Rich Evh1 Ligand 1Prel-1Proline-Rich Protein 73Rap1-Gtp-Interacting Adapter MoleculeRiamRetinoic Acid-Responsive Proline-Rich Protein 1Rarp-1 |
| Database Links | Reactome: R-HSA-354192Reactome: R-HSA-354194Reactome: R-HSA-372708Reactome: R-HSA-5674135Reactome: R-HSA-6802946Reactome: R-HSA-6802948Reactome: R-HSA-6802952Reactome: R-HSA-6802955Reactome: R-HSA-9649948Reactome: R-HSA-9656223 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCell ProjectionLamellipodiumCell JunctionFocal AdhesionCytoplasmCytoskeletonColocalizes With Ena/Vasp Proteins At Lamellipodia Tips And Focal AdhesionsAnd F-Actin At The Leading EdgeAt The Membrane SurfaceAssociatesVia The Ph DomainPreferentially With The Inositol PhosphatesPtdins(5)P And Ptdins(3)PThis Binding Appears To Be Necessary For The Efficient Interaction Of The Ra Domain To Ras-Gtpases |
| Alternative Antibody Names | Anti-Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting Protein antibodyAnti-Apbb1-Interacting Protein 1 antibodyAnti-Proline-Rich Evh1 Ligand 1 antibodyAnti-Prel-1 antibodyAnti-Proline-Rich Protein 73 antibodyAnti-Rap1-Gtp-Interacting Adapter Molecule antibodyAnti-Riam antibodyAnti-Retinoic Acid-Responsive Proline-Rich Protein 1 antibodyAnti-Rarp-1 antibodyAnti-APBB1IP antibodyAnti-PREL1 antibodyAnti-RARP1 antibodyAnti-RIAM antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
