| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-APBA1/MINT1 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 100kDa band observed in Human Brain (Cerebellum and Hippocampus) lysates (calculated MW of 92.9kDa according to NP_001154.2). Recommended concentration: 0.1-0.3µg/ml. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
APBA1 |
| Gene ID: |
320 |
| Uniprot ID: |
APBA1_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_001154.2 |
| Immunogen Sequence: |
EASHPSQDGKRQYK |
| Function | Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules. |
| Protein Name | Amyloid-Beta A4 Precursor Protein-Binding Family A Member 1Adapter Protein X11alphaNeuron-Specific X11 ProteinNeuronal Munc18-1-Interacting Protein 1Mint-1 |
| Database Links | Reactome: R-HSA-212676Reactome: R-HSA-6794361Reactome: R-HSA-9609736 |
| Cellular Localisation | CytoplasmPerinuclear RegionNucleusOnly About 5% Of The Protein Is Located In The NucleusIsoform 2: Golgi Apparatus |
| Alternative Antibody Names | Anti-Amyloid-Beta A4 Precursor Protein-Binding Family A Member 1 antibodyAnti-Adapter Protein X11alpha antibodyAnti-Neuron-Specific X11 Protein antibodyAnti-Neuronal Munc18-1-Interacting Protein 1 antibodyAnti-Mint-1 antibodyAnti-APBA1 antibodyAnti-MINT1 antibodyAnti-X11 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
