• Western blot analysis of lysates from COLO205 cells, using APAF-1-ALT Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of COLO205 cells using Apaf-1-ALT Polyclonal Antibody diluted at 1：500
  • Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using APAF-1-ALT Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Apaf-1-ALT Polyclonal Antibody diluted at 1：500

Anti-APAF1 antibody (289-338 aa) (STJ91620)

SKU:
STJ91620

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Apoptotic protease-activating factor 1 (289-338 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: APAF1
Gene ID: 317
Uniprot ID: APAF_HUMAN
Immunogen Region: 289-338 aa
Specificity: Apaf-1-ALT Polyclonal Antibody detects endogenous levels of Apaf-1-ALT protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human APAF-1-ALT at the amino acid range 289-338
Function Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Protein Name Apoptotic Protease-Activating Factor 1
Apaf-1
Database Links Reactome: R-HSA-111458
Reactome: R-HSA-111459
Reactome: R-HSA-111463
Reactome: R-HSA-111464
Reactome: R-HSA-6798695
Reactome: R-HSA-6803207
Reactome: R-HSA-8953750
Reactome: R-HSA-9627069
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Apoptotic Protease-Activating Factor 1 antibody
Anti-Apaf-1 antibody
Anti-APAF1 antibody
Anti-KIAA0413 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance