Anti-AP-1 complex subunit beta-1 antibody (11-29 aa) (STJA0040955)

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STJA0040955-100
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Short Description :Rabbit polyclonal anti-AP-1 complex subunit beta-1 (11-29 aa) for use in ICC, IHC-F, IHC-P and WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:ICC/IHC-F/IHC-P/WB
Host:Rabbit
Reactivity:Human/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:Mixed
Conjugation:Unconjugated
Purification:Whole serum
Dilution Range:WB 1:100-1:10000
IHC 1:1000-1:5000
Storage Instruction:Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at-20°C for a higher stability, and at 2-8°C with an appropriate antibacterial
Gene Symbol:AP1B1
Gene ID:162
Uniprot ID:AP1B1_HUMAN
Immunogen:A synthetic peptide (C-KKGEIFELKAELNSDKKEK) corresponding to the amino acids 11-29 of human AP-1 complex subunit beta-1 conjugated to diphtheria toxin has been used as the immunogen. The peptide is homologous with the corresponding sequence derived f
Immunogen Region:11-29 aa
Immunogen Sequence:Human
Specificity:This antibody has been shown to be specific for AP-1 complex subunit beta-1. Rat and human, other species have not yet tested.
Tissue Specificity Widely expressed.
Function Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
Protein Name Ap-1 Complex Subunit Beta-1
Adaptor Protein Complex Ap-1 Subunit Beta-1
Adaptor-Related Protein Complex 1 Subunit Beta-1
Beta-1-Adaptin
Beta-Adaptin 1
Clathrin Assembly Protein Complex 1 Beta Large Chain
Golgi Adaptor Ha1/Ap1 Adaptin Beta Subunit
Database Links Reactome: R-HSA-164940
Reactome: R-HSA-2132295
Reactome: R-HSA-432720
Reactome: R-HSA-432722
Cellular Localisation Golgi Apparatus
Cytoplasmic Vesicle
Clathrin-Coated Vesicle Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Component Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi Complex
Alternative Antibody Names Anti-Ap-1 Complex Subunit Beta-1 antibody
Anti-Adaptor Protein Complex Ap-1 Subunit Beta-1 antibody
Anti-Adaptor-Related Protein Complex 1 Subunit Beta-1 antibody
Anti-Beta-1-Adaptin antibody
Anti-Beta-Adaptin 1 antibody
Anti-Clathrin Assembly Protein Complex 1 Beta Large Chain antibody
Anti-Golgi Adaptor Ha1/Ap1 Adaptin Beta Subunit antibody
Anti-AP1B1 antibody
Anti-ADTB1 antibody
Anti-BAM22 antibody
Anti-CLAPB2 antibody

Information sourced from Uniprot.org

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