Anti-ANXA11 antibody (276-505) (STJ29559)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ANXA11 (276-505) antibody for use in WB, IF, ICC, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/IP/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ANXA11 |
| Gene ID | 311 |
| Uniprot ID | ANX11_HUMAN |
| Immunogen Region | 276-505 |
| Immunogen Sequence | FDIYEIKEAIKGVGTDEACL IEILASRSNEHIRELNRAYK AEFKKTLEEAIRSDTSGHFQ RLLISLSQGNRDESTNVDMS LAQRDAQELYAAGENRLGTD ESKFNAVLCSRSRAHLVAVF NEYQRMTGRDIEKSICREMS GDLEEGMLAVVKCLKNTPAF FAERLNKAMRGAGTKDRTLI RIMVSRSETDLLDIRSEYKR MYGKSLYHDISGDTSGDYRK ILLKICGGND |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 276-505 of human Annexin A11 (NP_001148.1). |
Additional Info
| Function | Binds specifically to calcyclin in a calcium-dependent manner. Required for midbody formation and completion of the terminal phase of cytokinesis. |
| Protein Name | Annexin A1156 Kda AutoantigenAnnexin XiAnnexin-11Calcyclin-Associated Annexin 50Cap-50 |
| Database Links | |
| Cellular Localisation | CytoplasmMelanosomeNucleus EnvelopeNucleusNucleoplasmCytoskeletonSpindleFound Throughout The Nucleoplasm At Interphase And During Mitosis Concentrates Around The Mitotic ApparatusElevation Of Intracellular Calcium Causes Relocalization From The Nucleoplasm To The Nuclear EnvelopeWith Little Effect On The Cytoplasmic PoolLocalization To The Nuclear Envelope Is Cell-Cycle Dependent |
| Alternative Antibody Names | Anti-Annexin A11 antibodyAnti-56 Kda Autoantigen antibodyAnti-Annexin Xi antibodyAnti-Annexin-11 antibodyAnti-Calcyclin-Associated Annexin 50 antibodyAnti-Cap-50 antibodyAnti-ANXA11 antibodyAnti-ANX11 antibody |
Information sourced from Uniprot.org