Anti-Anterior Gradient 2 antibody [ZN245] (STJA0033296)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenHuman recombinant protein fragment of human AGR2 (NP_006399) produced in E.coli.
General Information
| Short Description | Mouse monoclonal anti-Anterior Gradient 2 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ZN245 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 0.5-1.0 mg/mL |
| Purification | Affinity Chromatography |
| Dilution Range | IHC 1:50-1:100 |
| Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | AGR2 |
| Gene ID | 10551 |
| Uniprot ID | AGR2_HUMAN |
| Immunogen | Human recombinant protein fragment of human AGR2 (NP_006399) produced in E.coli. |
Additional Info
| Tissue Specificity | Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines. |
| Function | Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Promotes cell adhesion. |
| Protein Name | Anterior Gradient Protein 2 HomologAg-2Hag-2Hpc8Secreted Cement Gland Protein Xag-2 Homolog |
| Database Links | |
| Cellular Localisation | SecretedEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Anterior Gradient Protein 2 Homolog antibodyAnti-Ag-2 antibodyAnti-Hag-2 antibodyAnti-Hpc8 antibodyAnti-Secreted Cement Gland Protein Xag-2 Homolog antibodyAnti-AGR2 antibodyAnti-AG2 antibodyAnti-UNQ515 antibodyAnti-PRO1030 antibody |
Information sourced from Uniprot.org