Anti-ANO2 antibody (362-412 aa) (STJ195333)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ANO2 at the amino acid range 362-412
General Information
| Short Description | Rabbit polyclonal anti-Anoctamin-2 (362-412 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ANO2 |
| Gene ID | 57101 |
| Uniprot ID | ANO2_HUMAN |
| Immunogen | Synthesized peptide derived from the human ANO2 at the amino acid range 362-412 |
| Immunogen Region | 362-412 aa |
| Specificity | This antibody detects endogenous levels of ANO2 at Human/Mouse |
Additional Info
| Function | Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina. |
| Protein Name | Anoctamin-2Transmembrane Protein 16b |
| Database Links | Reactome: R-HSA-2672351Reactome: R-HSA-381753Reactome: R-HSA-9733458 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Anoctamin-2 antibodyAnti-Transmembrane Protein 16b antibodyAnti-ANO2 antibodyAnti-C12orf3 antibodyAnti-TMEM16B antibody |
Information sourced from Uniprot.org