Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Ankyrin repeat domain-containing protein 13A is suitable for use in Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ANKRD13A |
Gene ID: | 88455 |
Uniprot ID: | AN13A_HUMAN |
Specificity: | This antibody detects endogenous levels of ANKRD13A at Human, Mouse |
Immunogen: | Synthesized peptide derived from human ANKRD13A |
Function | Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. |
Protein Name | Ankyrin Repeat Domain-Containing Protein 13aProtein Ke03 |
Cellular Localisation | Cell MembraneLate EndosomeInteraction With Egfr May Enhance Association With The Cell Membrane |
Alternative Antibody Names | Anti-Ankyrin Repeat Domain-Containing Protein 13a antibodyAnti-Protein Ke03 antibodyAnti-ANKRD13A antibodyAnti-ANKRD13 antibody |
Information sourced from Uniprot.org