| Host: | Rabbit |
| Applications: | IHC/IF |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Ankyrin repeat domain-containing protein 11 (557-607 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC-P 1:50-200 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ANKRD11 |
| Gene ID: | 29123 |
| Uniprot ID: | ANR11_HUMAN |
| Immunogen Region: | 557-607 aa |
| Specificity: | This antibody detects endogenous levels of ANR11 at Human |
| Immunogen: | Synthesized peptide derived from the human ANR11 at the amino acid range 557-607 |
| Function | Chromatin regulator which modulates histone acetylation and gene expression in neural precursor cells. May recruit histone deacetylases (HDACs) to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation. Has a role in proliferation and development of cortical neural precursors. May also regulate bone homeostasis. |
| Protein Name | Ankyrin Repeat Domain-Containing Protein 11 Ankyrin Repeat-Containing Cofactor 1 |
| Cellular Localisation | Nucleus Localizes To Chromatin During Prometaphase |
| Alternative Antibody Names | Anti-Ankyrin Repeat Domain-Containing Protein 11 antibody Anti-Ankyrin Repeat-Containing Cofactor 1 antibody Anti-ANKRD11 antibody Anti-ANCO1 antibody |
Information sourced from Uniprot.org