• Western blot analysis of extracts of various cell lines, using ANKRD1 antibody (STJ11104705) at1:2000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-ANKRD1 antibody (1-130) [S4705RM] (STJ11104705)

SKU:
STJ11104705

£146.50 - £639.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Ankyrin Repeat Domain-Containing Protein 1 (1-130) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S4705RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ANKRD1
Gene ID: 27063
Uniprot ID: ANKR1_HUMAN
Immunogen Region: 1-130
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human ANKRD1 (NP_055206.2).
Immunogen Sequence: MMVLKVEELVTGKKNGNGEA GEFLPEDFRDGEYEAAVTLE KQEDLKTLLAHPVTLGEQQW KSEKQREAELKKKKLEQRSK LENLEDLEIIIQLKKRKKYR KTKVPVVKEPEPEIITEPVD VPTFLKAALE
Tissue Specificity Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells.
Function May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.
Protein Name Ankyrin Repeat Domain-Containing Protein 1
Cardiac Ankyrin Repeat Protein
Cytokine-Inducible Gene C-193 Protein
Cytokine-Inducible Nuclear Protein
Database Links Reactome: R-HSA-1989781
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Ankyrin Repeat Domain-Containing Protein 1 antibody
Anti-Cardiac Ankyrin Repeat Protein antibody
Anti-Cytokine-Inducible Gene C-193 Protein antibody
Anti-Cytokine-Inducible Nuclear Protein antibody
Anti-ANKRD1 antibody
Anti-C193 antibody
Anti-CARP antibody
Anti-HA1A2 antibody

Information sourced from Uniprot.org

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