| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | SRM5089 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Gene Symbol: | ANKRD1 |
| Gene ID: | 27063 |
| Uniprot ID: | ANKR1_HUMAN |
| Immunogen Region: | 1-130 aa |
| Immunogen Sequence: | MMVLKVEELVTGKKNGNGEA GEFLPEDFRDGEYEAAVTLE KQEDLKTLLAHPVTLGEQQW KSEKQREAELKKKKLEQRSK LENLEDLEIIIQLKKRKKYR KTKVPVVKEPEPEIITEPVD VPTFLKAALE |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human ANKRD1 Rabbit PolymAb® (NP_055206.2). |
| Tissue Specificity | Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells. |
| Function | May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. |
| Protein Name | Ankyrin Repeat Domain-Containing Protein 1Cardiac Ankyrin Repeat ProteinCytokine-Inducible Gene C-193 ProteinCytokine-Inducible Nuclear Protein |
| Database Links | Reactome: R-HSA-1989781 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Ankyrin Repeat Domain-Containing Protein 1 antibodyAnti-Cardiac Ankyrin Repeat Protein antibodyAnti-Cytokine-Inducible Gene C-193 Protein antibodyAnti-Cytokine-Inducible Nuclear Protein antibodyAnti-ANKRD1 antibodyAnti-C193 antibodyAnti-CARP antibodyAnti-HA1A2 antibody |
Information sourced from Uniprot.org
