Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Angiopoietin-Like Protein 8 (22-198) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ANGPTL8 |
Gene ID: |
55908 |
Uniprot ID: |
ANGL8_HUMAN |
Immunogen Region: |
22-198 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 22-198 of human ANGPTL8 (NP_061157.3). |
Immunogen Sequence: |
APMGGPELAQHEELTLLFHG TLQLGQALNGVYRTTEGRLT KARNSLGLYGRTIELLGQEV SRGRDAAQELRASLLETQME EDILQLQAEATAEVLGEVAQ AQKVLRDSVQRLEVQLRSAW LGPAYREFEVLKAHADKQSH ILWALTGHVQRQRREMVAQQ HRLRQIQERLHTAALPA |
Tissue Specificity | Predominantly expressed in liver. Also expressed in adipose tissues. |
Post Translational Modifications | Proteolytically cleaved at the N-terminus. |
Function | Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state. |
Protein Name | Angiopoietin-Like Protein 8BetatrophinLipasinRefeeding-Induced Fat And Liver Protein |
Database Links | Reactome: R-HSA-8963889 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Angiopoietin-Like Protein 8 antibodyAnti-Betatrophin antibodyAnti-Lipasin antibodyAnti-Refeeding-Induced Fat And Liver Protein antibodyAnti-ANGPTL8 antibodyAnti-C19orf80 antibodyAnti-RIFL antibodyAnti-UNQ599 antibodyAnti-PRO1185 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance