Anti-AMOTL1 antibody (441-490 aa) (STJ91593)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human AMOTL1 at the amino acid range 441-490
General Information
| Short Description | Rabbit polyclonal anti-Angiomotin-like protein 1 (441-490 aa) for use in IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AMOTL1 |
| Gene ID | 154810 |
| Uniprot ID | AMOL1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human AMOTL1 at the amino acid range 441-490 |
| Immunogen Region | 441-490 aa |
| Specificity | Angiomotin-L1 Polyclonal Antibody detects endogenous levels of Angiomotin-L1 protein. |
Additional Info
| Function | Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. |
| Protein Name | Angiomotin-Like Protein 1 |
| Database Links | Reactome: R-HSA-2028269 |
| Cellular Localisation | Cell JunctionTight Junction |
| Alternative Antibody Names | Anti-Angiomotin-Like Protein 1 antibodyAnti-AMOTL1 antibody |
Information sourced from Uniprot.org