Anti-AMIGO2 antibody (C-Term) (STJA0005769)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide corresponding to amino acids from the C-terminal region of mouse Alivin1
General Information
| Short Description | Rabbit polyclonal anti-Alivin1 (C-Term) for use in WB in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Antigen Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | PBS + 0.02% NaN3 |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AMIGO2 |
| Gene ID | 347902 |
| Uniprot ID | AMGO2_HUMAN |
| Immunogen | Synthetic peptide corresponding to amino acids from the C-terminal region of mouse Alivin1 |
| Immunogen Region | C-Term |
| Specificity | Reacts with the C-terminal region of mouse and rat Alivin1 |
Additional Info
| Function | Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas. |
| Protein Name | Amphoterin-Induced Protein 2Amigo-2Alivin-1Differentially Expressed In Gastric AdenocarcinomasDega |
| Database Links | Reactome: R-HSA-9013149Reactome: R-HSA-9013423 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinNucleusAssociated With Nucleus As Well As Plasma MembraneRestricted To Somata Of Cerebellar As Well As Hippocampal Neurons |
| Alternative Antibody Names | Anti-Amphoterin-Induced Protein 2 antibodyAnti-Amigo-2 antibodyAnti-Alivin-1 antibodyAnti-Differentially Expressed In Gastric Adenocarcinomas antibodyAnti-Dega antibodyAnti-AMIGO2 antibodyAnti-ALI1 antibody |
Information sourced from Uniprot.org